Mark Twain Brewing Company

422 North Main Street
Hannibal, MO 63401

573-406-1300

Welcome to Mark Twain Brewing Company

We take great pride in being located across the street from the boyhood home of Mark Twain, just off the banks of the Mississippi River in Hannibal, Missouri. And we take great pride in crafting beer as flavorful as the man himself.

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